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目的分析急性农药中毒病例的流行特征,摸清影响预后的危险因素,探讨其发病规律及可行的防治策略。方法通过回顾性收集2007年1月～2011年12月期间的306例急性农药中毒病例;采用自行设计的调查表,收集各个病例的各种资料。结果 306例患者中,有机磷中毒173例(56.5%)、拟除虫菊酯中毒49例(16.0%)、百草枯中毒81例(26.5%)、其他中毒3例(1.0%);影响预后的因素包括性别(OR=3.930)、中毒程度(OR=10.166)、毒物种类(OR=5.854)、氧气吸入(OR=0.211)、呼吸系统异常(OR=6.180)、发热(OR=7.182)、脉搏(OR=4.063)、肾功能(OR=4.670)、心电图检查(OR=2.272)等指标。结论摸清了急性农药中毒的流行特征,分析了影响预后的危险因素,并提出了急性农药中毒的预防和救治策略。
Objective To analyze the epidemiological characteristics of acute pesticide poisoning cases, to find out the risk factors affecting the prognosis, and to explore its pathogenesis and possible control strategies. Methods By retrospectively collecting 306 cases of acute pesticide poisoning during the period from January 2007 to December 2011, self-designed questionnaires were used to collect various data of each case. Results Of the 306 patients, 173 (56.5%) were organophosphorus poisoning, 49 (16.0%) were pyrethroid poisoning, 81 (26.5%) were paraquat poisoning and 3 were other poisoning (1.0%). The factors influencing the prognosis (OR = 3.930), poisoning (OR = 10.166), toxic species (OR = 5.854), oxygen inhalation (OR = 0.211), respiratory system abnormality OR = 4.063), renal function (OR = 4.670), ECG (OR = 2.272) and other indicators. Conclusion The epidemiological characteristics of acute pesticide poisoning were found out, the risk factors affecting prognosis were analyzed, and the prevention and treatment strategies of acute pesticide poisoning were put forward.