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目的了解随州地区HIV阳性孕产妇中的婴幼儿感染HIV的状况,探讨减少及阻断HIV母婴垂直传播的方法,为预防和控制HIV母婴垂直传播提供一些依据。方法收集2002-2008年随州地区自愿咨询的HIV阳性孕产妇及所产婴幼儿,对2004年后的HIV阳性孕产妇及其新生儿实施综合干预。结果随州市2002-2008年共发现15例孕产妇为HIV阳性,2例幼儿HIV阳性,经母婴传播感染比例为0.34%(2/591),自然传播率为13.33%(2/15)。2004年7月实施母婴阻断前的母婴传播途径感染比例为0.77%(2/260),其母婴自然传播率为28.6%(2/7);2004年7月实施母婴阻断后未发现经母婴传播的婴幼儿。结论随州市HIV的感染人群已由高危人群向普通人群转换,孕产妇人群中艾滋病的感染问题日趋严重,应引起高度重视;对孕妇提供AIDS自愿咨询检测服务和对HIV孕产妇采取综合性干预措施,可有效防止或阻断HIV母婴垂直传播的发生。
Objective To understand the status of HIV infection among infants and toddlers in HIV-positive pregnant women in Suizhou and to explore ways to reduce and block the vertical transmission of HIV in infants and toddlers. It provides some evidences for preventing and controlling the vertical transmission of HIV. Methods Voluntary HIV-positive pregnant women and infants born in Suizhou Prefecture from 2002 to 2008 were collected to implement comprehensive interventions on post-2004 HIV-positive pregnant women and their newborns. Results A total of 15 pregnant women were found to be HIV positive in Suizhou from 2002 to 2008. Two of them were HIV positive, with a rate of 0.34% (2/591) and a natural rate of 13.33% (2/15). The rate of mother-to-child transmission before mother-infant block was 0.77% (2/260) in July 2004 and 28.6% (2/7) in mother-infant. The mother-infant interruption After the mother and child were not found in infants and young children. Conclusion In Suizhou, the HIV infected population has been switched from the high-risk population to the general population. The HIV / AIDS infection in the pregnant women population is becoming more and more serious, which should be paid more attention to. Voluntary HIV counseling and testing services for pregnant women and comprehensive interventions for HIV and maternal , Can effectively prevent or block the vertical transmission of HIV mother and baby.