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对47例肾炎患儿进行t-PA:Ag、t-PA:A、PAI：A、D-Dimer、FDP-E和FDP共6项纤溶指标检测。结果提示：肾炎患儿存在明显纤溶活性升高；15例肾炎患儿经治疗后，随着症状改善，6项纤溶指标均恢复正常。提示：动态观察多项纤溶指标有助于肾炎患儿病情判断和疗效观察；FDP-E和D－Dimer相关分析表明，FDP-E可作为诊断肾炎患儿高凝状态的分子标志物之一。
47 cases of nephritis in children with t-PA: Ag, t-PA: A, PAI: A, D-Dimer, FDP-E and FDP were detected 6 fibrinolysis. The results suggest that there is an obvious increase of fibrinolytic activity in children with nephritis. After the treatment of 15 nephritis children, all 6 fibrinolytic indexes returned to normal with the improvement of symptoms. It is indicated that the dynamic observation of multiple fibrinolytic indexes is helpful to judge the condition of children with nephritis and to observe the curative effect.FDP-E and D-Dimer correlation analysis show that FDP-E can be used as one of the molecular markers to diagnose hypercoagulable state in children with nephritis .