论文部分内容阅读
本文对原发性高血压(EH)病人30例,正常人30例。观察其外周“压降”发生部位及其上下游血流动力学变化。结果显示:1.EH组外周血压显著下降部位发生于小动脉和微动脉,而正常对照组外周血压显著下降部位仅发生于毛细血管前微动脉,提示EH组总外周阻力血管段延长。2.EH组上游血流动力学异常表现为:(1)动脉血压升高,总外周阻力(TPR)和室壁应力(ESS)等后负荷增加引起左室肥厚(LVH)和舒张功能障碍;(2)动脉顺应性减退,壁剪切应力下降,壁张力增加和壁/腔比率增大。3.EH组微循环障碍表现:微血管压、流、阻异常,微循环储备功能减退,微血管病,加权积分值增加等。
In this paper, 30 cases of essential hypertension (EH) patients, 30 cases of normal. Observed its peripheral “pressure drop” the site of occurrence and its upstream and downstream hemodynamic changes. The results showed that: 1.EH group decreased significantly in peripheral arterial pressure occurred in the arterioles and arterioles, while the control group, a significant decline in peripheral blood pressure occurred only in pre-capillary arteries, suggesting that EH group of peripheral resistance vascular extension. The hemodynamic abnormalities in the upper part of the EH group were as follows: (1) elevated left ventricular hypertrophy (LVH) and diastolic dysfunction caused by increased arterial pressure, total peripheral resistance (TPR) and wall stress (ESS) 2) decreased arterial compliance, decreased wall shear stress, increased wall tension and increased wall / cavity ratio. 3.EH group microcirculation performance: microvascular pressure, flow, resistance abnormalities, microcirculation reserve dysfunction, microangiopathy, weighted integral value increases.