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迄今为止,鼻咽癌的诊断仍主要依赖于耳鼻咽喉科临床医生通过前鼻镜或后鼻镜检查发现肿瘤,然后经鼻腔或经口腔进行活检。由于鼻咽癌早期症状、体征不明显,并易于发生颈部转移,许多病人就诊或确诊时常已失之过晚。因此,寻求对这种恶性肿瘤的早期诊断的方法,仍然是鼻咽癌临床研究中需要解决的课题。现将国外有关近况综述如下。血清EBV抗体的检测关于EB病毒与鼻咽癌的密切关系、EB病毒在鼻咽癌病因中可能起的重要作用、EB病毒各种抗体的检测及其在不同病期、不同病理类型的鼻咽癌以及治疗后不同时期的变化规律,已进行过大量的研究。国内石善溶、唐忠怀、汪吉宝、陶正德等先后作过系统的综述。在这方面,人们最关心的是除了弄清鼻咽癌的病因、从根本上找到可能的预防手段外,还在于确定EB病毒抗体的检测能否真正成为早期、甚至亚临床
Until now, the diagnosis of nasopharyngeal carcinoma has remained largely dependent on otolaryngology clinicians finding tumors by anterior or post-nasal examination and then transnasally or trans-oral biopsies. Because of nasopharyngeal carcinoma of the early symptoms, signs are not obvious, and prone to neck metastasis, many patients often missed diagnosis or diagnosis. Therefore, to seek early diagnosis of this malignant tumor is still nasopharyngeal cancer clinical research needs to be addressed. The current foreign situation is summarized below. Detection of Serum EBV Antibodies The close relationship between Epstein-Barr virus and nasopharyngeal carcinoma may play an important role in the etiopathogenesis of nasopharyngeal carcinoma. The detection of various antibodies of Epstein-Barr virus and their different pathological types of nasopharynx at different stages Cancer and changes in different periods after treatment, a large number of studies have been conducted. Domestic stone Shan Rong, Tang Zhonghuai, Wang Jibao, Tao Zhengde has made a systematic review. In this regard, people are most concerned about in addition to clarify the etiology of nasopharyngeal carcinoma, fundamentally find possible preventive measures, but also to determine whether the detection of Epstein-Barr virus can truly become early, and even subclinical