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目的对胃肠道间质瘤诊疗的探讨。方法河北省邯郸市第一医院2009年至2011年例胃肠道间质瘤患者45例,对这些病例的诊断、检查、治疗及疗效回顾性分析。结果此次讨论的所有病例中43例患者酪氨酸激酶受体CD117呈阳性,占95.6%;28例CD34阳性患者,占75.6%,CD117、CD34均为阳性的患者24例,占53.3%。治疗方法以手术为主,所有病例无围手术期死亡,无严重并发症且痊愈出院,对40例患者随访,半年至3年。结论胃肠道间质瘤临床表现无显著特性,术前诊断率较低,免疫化验对此病起着独特的作用,主要的治疗方法为外科手术切除。
Objective To study the diagnosis and treatment of gastrointestinal stromal tumors. Methods Forty-five patients with gastrointestinal stromal tumors from 2009 to 2011 in Handan First Hospital of Hebei Province were retrospectively analyzed in diagnosis, examination, treatment and curative effect of these cases. Results Of all the cases discussed in this study, 43 patients had positive tyrosine kinase receptor CD117, accounting for 95.6%. Twenty-eight patients with CD34 positive accounted for 75.6%, while 24 patients (53.3%) had positive CD117 and CD34. Surgical treatment of the main treatment, no perioperative deaths in all cases, no serious complications and discharged, 40 patients were followed up, six months to three years. Conclusion Gastrointestinal stromal tumors have no significant clinical manifestations, the preoperative diagnosis rate is low, immunochemical tests play a unique role in the disease, the main treatment for surgical resection.