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目的观察奥美拉唑联合奥曲肽治疗酒精性胃炎致上消化道出血的临床疗效。方法在静卧、保持呼吸道通畅、暂禁食、补液抗休克的同时,奥美拉唑40 mg,静脉注射,2次/d,至出血停止3 d。奥曲肽0.1 mg+5%葡萄糖液20 ml,静脉注射,随之0.6 mg+5%葡萄糖液50 ml,每小时2 ml,泵入,至出血停止24 h。结果 19例患者24 h内出血停止,1例24~48 h出血停止,1例72 h未能控制转外科治疗。结论奥美拉唑联合奥曲肽治疗酒精性胃炎致上消化道出血疗效可靠,值得推广。
Objective To observe the clinical efficacy of omeprazole combined with octreotide in treating upper gastrointestinal bleeding caused by alcohol gastritis. Methods While lying still, keeping the airway open, temporarily stopping feeding and rehydration anti-shock, omeprazole 40 mg was intravenously injected twice daily until the bleeding stopped for 3 days. Octreotide 0.1 mg + 5% glucose solution 20 ml, intravenously, followed by 0.6 mg + 5% glucose solution 50 ml, 2 ml per hour, pumped into the bleeding to stop 24 h. Results Nineteen patients stopped bleeding within 24 h, one stopped bleeding within 24-48 h and one failed to control the surgical treatment in 72 h. Conclusion omeprazole combined with octreotide treatment of alcoholic gastritis caused by upper gastrointestinal bleeding is reliable and worth promoting.