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病毒性角膜炎是眼科常见病,病程长且易复发,严重者可以致盲。目前虽可用阿糖腺苷和碘苷(疱疹净)等抗病毒药物治疗,但这些抗代谢药物对防止复发无效,且可引起进行性地角膜损伤,结斑而影响视力。随着干扰素的发现,临床已应用干扰素治疗病毒性疾患。Romano(1977)用人纤维细胞干扰素滴眼治疗5例疱疹性角膜炎,均在4～7天痊愈。Jones(1976)报告用人白细胞干扰素滴眼治疗疱疹性角膜炎减少了复发。兰州生物制品研究所第二研究室于1980年10月试制成功人白细胞干扰素,第一医院眼科自1981年2月开始试用于治疗病
Viral keratitis is a common eye disease, long course and easy to relapse, severe cases can cause blindness. Although currently available adenosine and iodine (herpes net) and other antiviral drugs, but these antimetabolites to prevent relapse ineffective, and can cause progressive corneal damage, spot and affect vision. With the discovery of interferon, interferon has been clinically used to treat viral diseases. Romano (1977) treated 5 cases of herpes keratitis with human fibroblast interferon eye drops, all within 4 to 7 days. Jones (1976) reported that treatment of herpes keratitis with human leukopelitis reduced the recurrence. Lanzhou Institute of Biological Products second laboratory in October 1980 trial of human leukocyte interferon trial, the first hospital ophthalmology since February 1981 trial for the treatment of disease