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目的:分析高压氧治疗脑梗死的疗效及影响因素。方法:把58例脑梗死患者随机分成两组,每组29例,一组采用高压氧配合常规药物进行治疗,称为高压氧组;另一组采用常规药物进行治疗,称为常规组。两组患者在治疗期间每天均应用一次含有20ml复方丹参静脉注射液的液体,静脉滴注,并口服维生素E,其中,患有高血压者酌情进行降压治疗。对两组患者治疗前及治疗后的全血黏度、红细胞压积、血浆黏度以及纤维蛋白原进行分析比较。结果:两组患者经过一个月的治疗后,常规组总有效率为89.7%,高压氧组总有效率为93.1%,两组没有明显的差异(P>0.05),但是明显进步率以及基本痊愈率,高压氧组要显著优于常规组(P<0.01);采用高压氧配合常规药物治疗后,高压氧组患者的全血黏度、红细胞压积、血浆黏度以及纤维蛋白原比治疗前明显有所下降(P<0.05～0.01),而常规组患者治疗前后的差异性不大。结论:采用高压氧治疗脑梗死,可以有效降低患者的全血黏度、红细胞压积、血浆黏度以及纤维蛋白原,作用迅速,可以广泛使用。
Objective: To analyze the effect and influencing factors of hyperbaric oxygen on cerebral infarction. Methods: Fifty-eight patients with cerebral infarction were randomly divided into two groups (n = 29 in each group). One group was treated by hyperbaric oxygen combined with conventional drugs and named as hyperbaric oxygen group. The other group was treated by conventional drugs and was treated as conventional group. Two groups of patients in the treatment of daily application of a solution containing 20ml compound Salvia intravenous fluids, intravenous infusion, and oral vitamin E, of which, suffering from hypertension, as appropriate, antihypertensive treatment. The levels of whole blood viscosity, hematocrit, plasma viscosity and fibrinogen were compared before and after treatment in both groups. Results: After a month of treatment, the total effective rate was 89.7% in the conventional group and 93.1% in the HBO group. There was no significant difference between the two groups (P> 0.05), but the significant improvement rate and basic recovery Rate and hyperbaric oxygen group was significantly better than the conventional group (P <0.01); after hyperbaric oxygen combined with conventional drug therapy, the whole blood viscosity, hematocrit, plasma viscosity and fibrinogen in hyperbaric oxygen group were significantly higher than those before treatment (P <0.05 ~ 0.01), while the difference between the conventional group before and after treatment was not significant. Conclusion: Hyperbaric oxygen treatment of cerebral infarction, can effectively reduce the patient’s whole blood viscosity, hematocrit, plasma viscosity and fibrinogen, the role of rapid, can be widely used.