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目的：通过18例因甘露醇治疗引起急性肾功衰竭的脑出血患者早期局部肝素化和无肝素紧急血透治疗的临床观察，评价其疗效和临床应用价值。方法：紧急血透组18例采用体外小剂量肝素化或无肝素高血流量血造，并加强超滤脱水。非血透组12例，采用常规治疗。结果；血透组治愈17例，死亡1例，人均透析1.72次，未见诱发出血或凝血。对照组治愈2例，死亡10例（P＜0．001）。结论：提出本方法减少了肝素诱发出血危险，安全有效。此类患者所需血透次数少，显效快，宜早期紧急血透。
OBJECTIVE: To evaluate the efficacy and clinical value of early local heparinization and non-heparin-induced hemodialysis in 18 patients with cerebral hemorrhage caused by mannitol-induced acute renal failure. Methods: 18 cases of emergency hemodialysis group using low-dose in vitro heparin or heparin-free high blood flow, and strengthen the ultrafiltration dehydration. Non-hemodialysis group of 12 cases, using conventional treatment. Results Hemodialysis group cured 17 cases, 1 died, per capita dialysis 1.72 times, no bleeding or coagulation was found. Control group, 2 patients were cured, 10 patients died (P <0.001). Conclusion: This method is proposed to reduce the risk of heparin-induced bleeding and is safe and effective. Such patients need less hemodialysis, markedly effective, should be early emergency hemodialysis.