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目的:综述植物中几种酚酸物质止血与活血作用的研究进展,为对含酚酸物质的植物药进一步研究提供参考。方法:查阅国内外文献,总结、提炼和阐明酚酸物质止血、抗凝作用的研究现状和前景。结果:几种酚酸物质在植物中广泛存在,具有较好的止血、抗凝、保护心血管等作用。结论:几种酚酸物质具止血、活血或双向平衡调节作用,用于开发抗心脑血管疾病、外伤出血,崩漏下血,延缓衰老等药物具有良好的前景。
OBJECTIVE: To summarize the research progress on the effect of hemostatic and blood-activating of several phenolic acids in plants, and to provide references for the further study of phytochemicals containing phenolic acids. Methods: To review the literature at home and abroad, summarize, refine and elucidate the current situation and prospects of hemostatic and anticoagulant effects of phenolic acids. Results: Several phenolic acids were widely found in plants and had good effects on hemostasis, anticoagulation and cardiovascular protection. CONCLUSIONS: Several phenolic acids have hemostatic, blood-activating or bidirectional balance regulation. They are promising for the development of anti-cardiovascular and cerebrovascular diseases, traumatic hemorrhage, metrorrhagia, anti-aging and other drugs.