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目的:探讨未足月胎膜早破的临床特征和治疗策略。方法:回顾性分析河北省秦皇岛市妇幼保健院2005～2008年收治的未足月胎膜早破患者499例的临床资料。结果:未足月胎膜早破的发病率是3.1%;发生未足月胎膜早破的相关因素依次是感染、既往早产或流产史、子宫张力高、胎膜受力不均等;其围生儿并发症以早产、胎儿窘迫、新生儿呼吸窘迫综合征为主;其围生儿结局与孕周直接相关。结论:胎膜早破是早产的主要原因。若临床无感染征象,应尽量保胎治疗至34周,适时终止妊娠。
Objective: To investigate the clinical features and treatment strategies of preterm premature rupture of membranes. Methods: The clinical data of 499 cases of premature rupture of membranes from 2005 to 2008 in Qinhuangdao Municipal Maternal and Child Health Hospital of Hebei Province were analyzed retrospectively. Results: The incidence of premature rupture of membranes was 3.1%. The related factors of premature rupture of membranes were infection, previous history of premature or abortion, high uterine tension and unequal fetal membrane force. Neonatal complications of preterm birth, fetal distress, neonatal respiratory distress syndrome based; their perinatal outcome and gestational age are directly related. Conclusion: Premature rupture of membranes is the main reason for premature delivery. If no clinical signs of infection, should try to protect the fetus to 34 weeks, timely termination of pregnancy.