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目的分析脑卒中急性期睡眠障碍原因。方法回顾性总结72例患者的临床、影像学、实验室检查及治疗与转归。结果脑卒中急性期睡眠障碍可能与以下因素有:(1)损害下丘脑或第三脑室侧壁;(2)直接损害睡眠与觉醒系统;(3)脑卒中后神经递质失调,如5-羟色胺下降;(4)社会心理因素;(5)环境因素;(6)精神疾病;(7)药物。结论脑卒中后睡眠障碍与5羟色胺下调有关,也与社会心理因素及环境因素有关。
Objective To analyze the causes of sleep disorders in the acute stage of stroke. Methods The clinical, imaging, laboratory tests, treatment and prognosis of 72 patients were retrospectively reviewed. Results In the acute phase of stroke, sleep disorders may be caused by the following factors: (1) damaging the lateral hypothalamus or the third ventricle, (2) directly impairing the sleep and wakefulness system, (3) neurotransmitters after stroke, such as 5- Serotonin decreased; (4) psychosocial factors; (5) environmental factors; (6) mental illness; (7) drugs. Conclusion After stroke, sleep disturbance is related to the down-regulation of serotonin, but also to the social and psychological factors and environmental factors.