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慢性吸烟与癌症发病有明显的关系已被人们广泛接受,但慢性吸烟对消化系统的影响还不为人们所重视。作者用特异的放免技术,检测了尼古丁慢性处理对具有胃瘘和胰瘘的清醒大鼠胰腺外分泌的影响及餐后胃泌素和CCK的释放。结果发现,通过胃管输入食物可以明显刺激正常和尼古丁处理大鼠血浆胃泌素水
Chronic smoking and cancer incidence have obvious relationship has been widely accepted, but the impact of chronic smoking on the digestive system is not valued. The authors used a specific radioimmunoassay technique to examine the effects of chronic nicotine treatment on pancreatic exocrine and postprandial gastrin and CCK release in conscious rats with gastrostomy and pancreatic fistulae. The results found that the food through the stomach tube can significantly stimulate the normal and nicotine-treated rats plasma gastrin water