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目的:分析急性早幼粒细胞白血病(APL)合并弥散性血管内凝血(DIC)的临床治疗及效果开展系统研究。方法:对2011年1月至2016年3月江门市中心医院血液内科接收的56例初治急性早幼粒细胞性白血病(APL)合并DIC患者的临床治疗情况进行回顾分析,并对纠正患者和死亡患者的相关因素进行对比分析。结果:本组56例患者在治疗之后,DIC得到纠正52例,死亡4例。结论:早期对DIC进行积极、对症治疗,可有效减少APL的早期死亡,提高患者的生存质量。
Objective: To analyze the clinical effects and treatment of acute promyelocytic leukemia (APL) and disseminated intravascular coagulation (DIC). Methods: The clinical data of 56 cases of newly diagnosed acute promyelocytic leukemia (APL) combined with DIC received by Department of Hematology, Jiangmen Central Hospital from January 2011 to March 2016 were retrospectively analyzed. Related factors of death patients were compared. Results: After treatment, 56 cases of DIC were corrected in 52 cases and 4 died. Conclusion: The positive and symptomatic treatment of DIC early can effectively reduce the early death of APL and improve the quality of life of patients.