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冒气止痛丸为一常用中成药,由香附及高良姜组成,具有理气安胃、散气止痛的功效,主治肝郁气滞引起胃寒作痛、两胁胀满、暖气吞酸等。因该品易霉变,使r-射线照射以利保藏,但不知照射后药性是否有变。据此我们对本品照射前后进行了以下的对比实验。一、对小鼠镇痛作用的影响:热板法,取18～22g的小鼠45只,随机分成三组,由腹腔分别注入照射、未照射冒气止痛丸水煎剂及盐酸吗啡,并于用药后1/2°、2°及3°测各组痛阈值。结果表明:照射品与未照品均有较明显的镇痛效应,(P<0.01),且两者间无显著性
Qi Feng Zhi Tong Wan is a commonly used proprietary Chinese medicine. It is composed of Cyperus rotundus and Galangal. It has the effects of regulating Qi and stomach, and relieves pain by gas. Indications of liver Qi qi stagnation cause cold aches in the stomach, two threatening fullness, and so on. Because the product is susceptible to mildew, r-rays are irradiated to facilitate preservation, but it is not known whether the drug properties change after irradiation. Based on this, we conducted the following comparative experiments before and after irradiation of this product. First, the effect of analgesic effects on mice: hot plate method, take 18 ~ 22g of mice 45, were randomly divided into three groups, from the abdominal cavity were injected into the irradiation, no radiation Pizhizhitong pill decoction and morphine hydrochloride, and The pain threshold of each group was measured at 1/2°, 2° and 3° after administration. The results showed that both the irradiated product and the untreated product had significant analgesic effect (P<0.01), and there was no significant difference between the two.