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组学技术是近年来在生物医学研究领域快速发展和受到高度重视的现代技术分析手段,主要包括基因组学、蛋白质组学和代谢组学,对肿瘤等疾病的发生机制及生物标志物的探索有很重要的价值。目前对肿瘤的早期诊断技术主要是对高危人群进行肿瘤标志物的普查,而很多肿瘤标志物的特异性和敏感性均不高,容易产生假阳性结果。这就为寻找更好的早期肿瘤诊断方法提出了新的要求,而组学技术的发展,为肿瘤的早期临床诊断开创了新的技术平台。虽然组学技术在肿瘤的早期诊断中表现了巨大的发展前景,但用于临床诊断和高危人群的筛查还有待深入研究。随着三种组学技术的不断发展,其在肿瘤的早期诊断中必将发挥重要的作用。本文重点围绕组学技术在肿瘤临床诊断中的研究及应用前景进行概述。
The technology of group study is a modern technical analysis method that has been rapidly developed and highly valued in the field of biomedical research in recent years. It mainly includes genomics, proteomics and metabonomics, the mechanism of tumor and other biomarkers Very important value. At present, the early diagnosis of cancer mainly focuses on the screening of cancer markers in high-risk groups. However, the specificity and sensitivity of many tumor markers are not high, which may easily lead to false-positive results. This put forward new requirements for finding a better method of early tumor diagnosis, and the development of omics technology opens a new technological platform for the early clinical diagnosis of tumors. Although omics technology in the early diagnosis of tumors showed tremendous development prospects, but for clinical diagnosis and screening of high-risk groups remains to be further studied. With the continuous development of the three omics technologies, they will play an important role in the early diagnosis of tumors. This article focuses on the study of omics technology in the clinical diagnosis of cancer and its application prospects.