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目的观察布地奈德雾化吸入治疗慢性阻塞性肺病急性加重期(AECOPD)的疗效。方法将67例患者随机分为治疗组35例和对照组32例,2组患者均接受吸氧、抗感染、化痰、雾化吸入沙丁胺醇等常规治疗,治疗组于常规治疗基础上加用布地奈德雾化吸入,比较两组间的疗效。结果治疗组和对照组治疗后FEV1、PaO2、PaCO2较治疗前改善,两者差异有统计学意义(P<0.05);而治疗组治疗后FEV1、PaO2、PaCO2较对照组改善更明显,两者差异有统计学意义(P<0.05)。结论布地奈德雾化吸入治疗AECO-PD,能改善肺功能和血气,疗效较好。
Objective To observe the efficacy of inhaled budesonide in the treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods Sixty-seven patients were randomly divided into treatment group (n = 35) and control group (n = 32). Patients in both groups received conventional therapy such as inhalation of oxygen, anti-infection, phlegm and inhalation of salbutamol. Ned inhalation, compared the efficacy of the two groups. Results The FEV1, PaO2 and PaCO2 in the treatment group and the control group were significantly improved after treatment compared with those before treatment (P <0.05), while the FEV1, PaO2 and PaCO2 in the treatment group improved more significantly than those in the control group The difference was statistically significant (P <0.05). Conclusion Budesonide inhalation treatment of AECO-PD, can improve lung function and blood gas, the effect is better.