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目的:比较氯沙坦、贝那普利对早期糖尿病肾病的治疗效果。方法;将30例早期糖尿病肾病患者随机分为1组氯沙坦和贝那普利各15例,疗程期为5周,治疗前后分别测定尿素氮(Bun)、肌酐(CRe)、尿酸(UA),治疗中观察比较两种药物不良反应。结果:两组疗效相近,氯沙坦组不良反应发生率明显低于贝那普利组。结论:氯沙坦比贝那普利治疗糖尿病肾病更安全有效。
Objective: To compare the therapeutic effect of losartan and benazepril on early diabetic nephropathy. Methods Thirty patients with early stage diabetic nephropathy were randomly divided into 1 group and 15 losartan and benazepril respectively. The course of treatment was 5 weeks. Before and after treatment, the levels of blood urea nitrogen (Bun), creatinine (CRe), uric acid ), Observed in the treatment of adverse reactions of two drugs. Results: The two groups of similar efficacy, losartan adverse reaction rate was significantly lower than the benazepril group. CONCLUSION: Losartan is safer and more effective than benazepril in the treatment of diabetic nephropathy.