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目的:探讨和分析中西医结合治疗淤胆型肝炎的临床价值。方法:将120例符合淤胆型肝炎诊断标准的患者按1∶1随机分成对照组和实验组。对照组仅应用常规西医方法治疗,实验组在其基础上加用中药汤剂,疗程为4～12周。比较两者治疗前、后肝功能指标及症状的变化。结果:两组症状均消失或明显改善;实验组治疗的总体有效率为83.3%,对照组仅为61.7%,两者比较有显著性差异(P<0.05)。两组治疗前、后TBILI、ALT、AST、ALP、GGT明显减低,其差异均有统计学意义(P<0.05);实验组治疗后TBILI、ALT、AST、ALP、GGT明显低于对照组,且差异有统计学意义(P<0.05)。结论:中西医结合治疗淤胆型肝炎疗效显著,治疗效果稳定且无副作用,该方法值得临床应用和推广。
Objective: To investigate and analyze the clinical value of integrated traditional Chinese and western medicine in the treatment of cholestatic hepatitis. Methods: One hundred and twenty patients who meet the diagnostic criteria of cholestatic hepatitis were randomly divided into control group and experimental group. The control group only treated with conventional Western medicine, the experimental group on the basis of the use of traditional Chinese medicine decoction, the course of treatment is 4 to 12 weeks. Compare the changes of liver function indexes and symptoms before and after treatment. Results: The symptoms disappeared or significantly improved in both groups. The overall effective rate was 83.3% in the experimental group and 61.7% in the control group. There was significant difference between the two groups (P <0.05). The levels of TBILI, ALT, AST, ALP and GGT in the two groups were significantly decreased after treatment (P <0.05). The TBILI, ALT, AST, ALP and GGT in the experimental group were significantly lower than those in the control group And the difference was statistically significant (P <0.05). Conclusion: Integrative treatment of cholestatic hepatitis has significant curative effect and stable therapeutic effect without side effects. This method is worthy of clinical application and promotion.