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对甘糖酯(PGMs)和藻酸双酯钠(PSS)治疗急性脑梗死的临床疗效和实验室变化进行了对比研究,发现PGMS治疗急性脑梗死的临床疗效虽优于PSS,但无统计学意义,可能与病例少有关。对患者的血脂、血粘度和凝血指标和变化进行了对比,发现PGMS的降血脂、降血粘度的作用优于PSS,而抗凝血作用则低于PSS。在治疗过程中PGMS无一例出现毒副作用。研究结果表明,PGMS治疗急性脑梗死的临床疗效、实验室变化优于PSS,而且无毒副反应,值得临床推广应用。
The clinical efficacy and laboratory changes of PGMs and PSS in patients with acute cerebral infarction were compared and found PGMS treatment of acute cerebral infarction is superior to PSS in clinical efficacy, but no statistical Meaning, may be less related to the case. The blood lipid, blood viscosity and coagulation indexes and changes of patients were compared. It was found that the effect of blood lipid lowering and blood viscosity lowering of PGMS was better than that of PSS and the anticoagulant effect was lower than that of PSS. PGMS in the course of treatment without any side effects. The results show that, PGMS in the treatment of acute cerebral infarction clinical efficacy, laboratory changes than PSS, and non-toxic side effects, it is worthy of clinical application.