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目的:总结部分脾栓塞治疗肝硬化脾功能亢进的临床经验及疗效。方法:对33例肝硬化合并脾功能亢进的患者行脾动脉超选择插管栓塞大部分脾动脉,栓塞程度50%~80%,对比观察手术前后外周血象的变化。结果:栓塞后血白细胞平均值由3.1×109/L升至4.6×109/L,红细胞平均值由2.2×1012/L升至3.6×1012/L,血小板平均值由47×109/L升至108×109/L。结论:部分脾栓塞可有效控制肝硬化并发的脾功能亢进,明显改善外周血象,但应严格控制脾栓塞的范围。
Objective: To summarize the clinical experience and curative effect of partial splenic embolization in the treatment of liver cirrhosis and hypersplenism. Methods: Thirty-three patients with cirrhosis and hypersplenism underwent supersembolization of the splenic artery to embolize most of the splenic arteries. The degree of embolization was 50% -80%. The changes of peripheral blood before and after surgery were observed. Results: After embolization, the mean leukocyte count increased from 3.1 × 109 / L to 4.6 × 109 / L, the average value of erythrocytes increased from 2.2 × 1012 / L to 3.6 × 1012 / L, and the mean platelet count increased from 47 × 109 / L to 108 × 109 / L. Conclusion: Some splenic embolization can effectively control hypersplenism associated with cirrhosis and improve peripheral blood, but the scope of splenic embolism should be strictly controlled.