Epigenetic changes associated with oocyte aging

来源 :中国科学：生命科学英文版 | 被引量 : 0次 | 上传用户：jql

【摘要】

：

It is well established that the decline in female reproductive outcomes is related to postovulatory aging of oocytes and advanced maternal age.Poor oocyte quali

【作者】

：

SCHATTEN Heide MA JunYu SCHATT

【机构】

：

StateKeyLaboratoryofReproductiveBiology,DepartmentofAnimalSciences,DepartmentofVeterinaryPathoiology

【出处】

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中国科学：生命科学英文版

【发表日期】

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2012年8期

【关键词】

：

表观遗传学细胞老化遗传变化卵母细胞质量 DNA甲基化组蛋白乙酰化遗传完整性老化过程 fertility advanced maternal age

【基金项目】

：

supported in part by the National Natural Science Foundation of China （Grant No. 81100422）, National Basic Research Program of China （Grant Nos. 2012CB944404 and 2011CB944501）

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It is well established that the decline in female reproductive outcomes is related to postovulatory aging of oocytes and advanced maternal age.Poor oocyte quality is correlated with compromised genetic integrity and epigenetic changes during the oocyte ag

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Epigenetic changes associated with oocyte aging

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