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目的探索以CT图像为基础构建动脉血流动力学模型的技术方法,对颈动脉狭窄局部进行计算血流动力学(computationalfluid dynamics,CFD)数值模拟。方法以CT图像为基础进行颈动脉三维几何建模,依据MRI测量的模型出入口血流速度确定数值模拟的边界条件。结果数值模拟结果包括狭窄颈动脉内的速度场和壁面剪应力(wall shear stress,WSS)分布,可见狭窄段血管WSS增高,且在狭窄邻近区域出现新的血液逆流区(对应低或振荡的WSS)。结论以CT图像为基础的CFD技术是在体评价人狭窄颈动脉内血流动力学状况与颈动脉斑块之间关系的有效方法。
Objective To explore a method of constructing arterial hemodynamics based on CT images and to perform computational computational fluid dynamics (CFD) numerical simulation of the carotid stenosis. Methods Three-dimensional geometric modeling of carotid artery was performed on the basis of CT images. The boundary conditions of numerical simulation were determined based on the velocity of blood flow at the entrance and exit of the model measured by MRI. Results The results of numerical simulation included the distribution of velocity field and wall shear stress (WSS) in the narrow carotid artery, showing an increase of WSS in the stenosis segment and a new area of hemorrhagic reflux in the stenosis (corresponding to low or oscillating WSS ). Conclusion The CFD technique based on CT images is an effective method to evaluate the relationship between the hemodynamics and the carotid plaque in the narrow carotid artery.