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目的探讨中西医结合治疗下肢深静脉血栓(deep venous thrombosis,DVT)的效果。方法选择2011年3月—2012年9月收治的DVT患者60例,随机分为对照组和观察组各30例。对照组发病早期患肢抬高30°左右静卧,严禁推拿、按摩、热敷等,有炎症者适当应用抗生素,并辅以小剂量尿激酶溶栓抗凝,每次(20~30)万U,溶于生理盐水500 ml中于患肢足背静脉缓慢滴入,每日1次,一般用药1~2周。静脉滴注低分子右旋糖酐500 ml、复方丹参注射液40 ml,每日1次,15 d为1个疗程,1个疗程后评价疗效。用药期间注意监测凝血指标,及时调整药量或停药。观察组在对照组基础上加自拟破瘀通脉汤口服,水煎服,日1剂,15 d为1个疗程,间隔5 d后进行第2个疗程。配合冰黄散外敷,每日1次。口服中药治疗2个疗程后评价疗效。计数资料采用χ2检验,P<0.05为差异有统计学意义。结果总有效率对照组70.0%,观察组96.7%,两组比较差异有统计学意义(P<0.05)。结论采用中西医结合的方法治疗DVT效果优于单纯西医治疗,值得临床推广应用。
Objective To explore the effect of treating acute venous thrombosis (DVT) by combining traditional Chinese and western medicine. Methods Sixty patients with DVT admitted from March 2011 to September 2012 were randomly divided into control group and observation group of 30 cases. In the control group, the affected limbs were raised at about 30 ° in the early stage of the disease and were allowed to lie on their knees. Massage, hot compress and other antibiotics were appropriately used. Inflammation was supplemented with thrombolysis and anticoagulation with small doses of urokinase (20-30) , Dissolved in saline 500 ml in the limb dorsal vein slowly drip, 1 day, the general medication for 1 to 2 weeks. Intravenous infusion of low molecular weight dextran 500 ml, compound Danshen injection 40 ml, day 1, 15 d for a course of treatment, a course of treatment after evaluation. Pay attention to monitoring blood coagulation indicators during medication, timely adjustment of dose or withdrawal. On the basis of the control group, the observation group was treated with oral administration of Ruoyu Tongmai Decoction orally, Shuijianbi, day 1, 15 days for a course of treatment, the second course after 5 days. Combined with ice Huang San, daily 1. After oral administration of traditional Chinese medicine to evaluate the efficacy of 2 courses. Count data using χ2 test, P <0.05 for the difference was statistically significant. Results The total effective rate was 70.0% in the control group and 96.7% in the observation group, with significant difference between the two groups (P <0.05). Conclusion The treatment of DVT by integrated traditional Chinese and western medicine is superior to western medicine alone and is worthy of clinical application.