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目的观察依那普利联合氯沙坦对高血压伴心功能不全患者左心功能的影响情况。方法选取2015年4月~2016年4月我院门诊收治的高血压伴心功能不全患者168例作为研究对象,随机分为参照组与联合组,各84例;参照组应用依那普利治疗高血压伴心功能不全,联合组应用依那普利加联合氯沙坦进行治疗高血压伴心功能不全,比较观察治疗半年后两组患者的超声心动图的改善情况,以分析药物对患者左心功能的影响结果。结果相比联合组与参照组的超声心动图改善情况,联合组患者的血压、左室结构及左心功能及NYHA心功能分级均显著优于参照组,差异有统计学意义(P<0.05)。结论依那普利联合氯沙坦对高血压伴心功能不全患者的左心功能有显著的改善影响,此联合疗法的应用价值深远且影响效果佳。
Objective To observe the effect of enalapril plus losartan on left ventricular function in hypertensive patients with cardiac dysfunction. Methods A total of 168 hypertensive patients with cardiac dysfunction admitted from our hospital from April 2015 to April 2016 were selected as study subjects and randomly divided into reference group and combined group, 84 cases in each group. The control group was enalapril Hypertension with cardiac insufficiency, combined with enalapril plus losartan for the treatment of hypertension with cardiac insufficiency, compared to observe the treatment of two groups of patients after echocardiography to improve the situation in order to analyze the drug left heart Effect of function result. Results Compared with the control group, the blood pressure, left ventricular structure, left ventricular function and NYHA functional class in the combined group were significantly better than those in the reference group (P 0. 05) . Conclusion Enalaprol combined with losartan can significantly improve the left ventricular function in hypertensive patients with cardiac insufficiency. The combination therapy is of far-reaching value and has a good effect.