论文部分内容阅读
目的研究某体检人群动脉弹性与血压、血清蛋白的关系。方法选择2014年7月在中国中医科学院广安门医院南区的体检者304例,询问病史、测量身高、体重、体重指数(BMI)、血压等,检测血常规、生化等指标,应用欧姆龙BP-203RPEⅢ动脉硬化检测仪检测体检人群的动脉弹性,根据肱踝脉搏波传导速度(baPWV)分为动脉正常组(117例),轻度硬化组(112例)与硬化组(75例),将3组临床指标比较研究。结果 3组收缩压(SBP)比较,轻度动脉硬化组、高度动脉硬化组均与动脉正常组比较,差异有统计学意义(P<0.01);3组舒张压(DBP)相比,轻度硬化组与硬化组与高度动脉动脉正常组比较,差异有统计学意义(P<0.01);3组血清白蛋白(ALB)相比,动脉正常组与轻度动脉硬化组、轻度动脉硬化组与高度动脉硬化组比较差异有统计学意义(P<0.05);3组血清球蛋白(GLB)相比,动脉正常组与轻度动脉硬化组比较差异有统计学意义(P<0.05)。相关性分析:3组年龄、SBP、DBP、GLB与baPWV呈正相关;ALB与baPWV呈负相关;而TP则与baPWV无相关性。结论血清ALB、GLB可用于早期估测动脉的弹性。应加强对老年人动脉弹性的检测,预防动脉硬化的发生。
Objective To study the relationship between arterial elasticity and blood pressure and serum protein in a medical examination population. Methods A total of 304 physical examinations were performed in July 2014 in Guang’anmen Hospital of the Chinese Academy of Chinese Medical Sciences to investigate the medical history, height, weight, body mass index (BMI) and blood pressure. Blood samples were collected for blood biochemical tests. 203RPEⅢAtherosclerosis detector was used to detect the arterial elasticity of the physical examination group and divided into normal arterial group (117 cases), mild sclerosis group (112 cases) and sclerosis group (75 cases) according to brachial-ankle pulse wave velocity (baPWV) Group of clinical indicators comparative study. Results Compared SBP in mild arteriosclerosis group and high arterial group with normal arterial group, the difference was statistically significant (P <0.01). Compared with DBP, mild Compared with normal arterial group, the difference was statistically significant (P <0.01). Compared with normal group, the level of serum albumin (ALB) in normal group and mild arteriosclerosis group, mild arteriosclerosis group (P <0.05). There was significant difference between the normal group and mild atherosclerosis group (P <0.05) compared with the GLB group. Correlation analysis: There was a positive correlation between age, SBP, DBP, GLB and baPWV, ALB and baPWV, but TP had no correlation with baPWV. Conclusions Serum ALB and GLB can be used to estimate arterial elasticity early. Should be strengthened in the detection of arterial elasticity in the elderly to prevent the occurrence of atherosclerosis.