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目的 :探讨提高胃原发恶性淋巴瘤的早期诊断率和长期生存率的方法。方法 :对经手术和病理确诊的 10例胃原发性恶性淋巴瘤进行分析。结果 :10例经胃镜活检病理证实 ,16例均手术病理证实 ,随访 2 2例 ,5年生存率 5 0 % (11例 )。结论 :胃原发性恶性淋巴瘤的临床表现无特异性 ,胃镜检查必须深挖多取才能得到阳性结果 ,结合 X线及活检组织免疫组化检查可提高早期诊断率。治疗以手术后化疗 (CHOP方案 )为主 ,清除 HP是治疗的关键 ,其预后与临床分期有关。
Objective: To explore methods to improve the early diagnosis rate and long-term survival rate of gastric primary malignant lymphoma. Methods : Analysis of 10 cases of primary malignant lymphoma of the stomach confirmed by surgery and pathology. Results : 10 cases were confirmed by gastroscope biopsy. 16 cases were confirmed by pathology. Follow-up was 22 cases. The 5-year survival rate was 50% (11 cases). Conclusion : The clinical manifestations of primary malignant lymphoma of the stomach are non-specific, and gastroscope examination must be carried out to obtain positive results. Combined with X-ray and biopsy, immunohistochemical examination can improve the early diagnosis rate. Treatment is based on postoperative chemotherapy (CHOP regimen). Removal of HP is the key to treatment, and its prognosis is related to clinical stage.