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目的 探讨老年人胃癌癌细胞浸润深度与癌周肥大细胞（ＭＣ） 的关系。方法 用俾士麦棕染色观察１０３ 例老年人胃癌和７２ 例青年人胃癌癌周ＭＣ。结果 老年人胃癌累及浆膜病例少于青年人胃癌（ Ｐ＜ ０－０１） ； 而癌周ＭＣ计数均数≥２３ 个ＨＰＦ的病例多于青年人胃癌（ Ｐ＜０－０１） 。结论 老年人胃癌癌周ＭＣ密度较高， 可能是其累及浆膜相对较少的原因之一。
Objective To investigate the relationship between the depth of invasion of gastric cancer cells and the surrounding mast cells (MC). METHODS: 103 cases of elderly gastric cancer and 72 cases of gastric cancer were observed by using brown wheat brown dye. Results Elderly patients with gastric cancer involving serosa were less than young patients with gastric cancer (P<0-01). However, the number of cancer patients with mean ≥23 HPF was more than that of young patients with gastric cancer (P<0-01). Conclusions The high density of gastric cancer in elderly patients may be one of the reasons for the relatively small number of serosa.