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目的 探讨老年人脑卒中后痴呆的危险因素。方法 对 2 5 8例资料完整的老年脑卒中患者进行了 3个月随访评价 ,包括临床神经学和神经心理学测试 ,对研究资料先进行单因素分析 ,然后进行多因素非条件Lo gistic回归模型分析。 结果 脑卒中后痴呆发生率为 32 2 %。经分析筛选出多灶病变、左侧及双侧病变、脑萎缩、年龄、高血压、以往脑血管病病史、大面积出血或梗死 8个因素为脑卒中后痴呆危险因素。结论 老年人脑卒中后痴呆由多种因素决定 ,它不仅与病灶部位、数目、大小及发病次数有关 ,亦与脑卒中患者基础脑功能状态有关。
Objective To explore the risk factors of post-stroke dementia in the elderly. Methods A total of 258 elderly patients with senile stroke were evaluated with 3-month follow-up, including clinical neuropsychological tests and neuropsychological tests. Univariate analysis of the data was performed prior to the multivariate non-conditional Lo gistic regression model analysis. Results The incidence of post-stroke dementia was 32 2%. After analysis, the risk factors of post-stroke dementia were selected from the analysis of multifocal lesion, left and bilateral lesions, brain atrophy, age, hypertension, previous history of cerebrovascular disease, large area bleeding or infarction. Conclusion Dementia after stroke in the elderly is determined by a variety of factors. It is not only related to the location of the lesion, the number, the size and the number of onset, but also the basic brain function of patients with stroke.