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一、病因感染性休克(以下简称感休)主要是由细菌和它的毒素所引起。发生率在过去25年中增加了20倍。死亡率为25～30％,合并原有疾病者死亡率高达70％。感休发生率的增加与严重创伤、移植、糖尿病、高龄及癌症等重危病人存活时间的延长、手术种数和范围的扩大、高营养静脉导管和导尿管留置时间过长,以及免疫抑制剂和糖皮质的应用增多等因素有关。在外科疾病其病因以化脓性胆管炎、弥漫性腹膜炎、纹窄性肠梗阻最多见;其次为尿路感染重度烧伤。致病菌绝大多数为G(一)杆菌。感染来源以胃肠道最多占80％,泌尿生殖系占13％,其他占7％。导致休克的败血症中,需氧G(一)杆菌占50％,拟杆菌
First, the cause of septic shock (hereinafter referred to as flu) is mainly caused by bacteria and its toxins. The incidence has increased 20 times over the past 25 years. The mortality rate is 25 to 30%, with the mortality rate of the original disease up to 70%. The increased incidence of flu and the prolonged survival of critically ill patients such as severe trauma, transplantation, diabetes, advanced age and cancer, the expansion of the number and scope of surgeries, prolonged periods of high-nutrition intravenous catheters and catheterization, and immunosuppression Increased use of agents and glucocorticoid and other factors. The causes of surgical diseases in purulent cholangitis, diffuse peritonitis, narrow lines of the most common intestinal obstruction; followed by severe urinary tract infection burns. The vast majority of pathogens G (a) bacilli. Sources of infection to the gastrointestinal tract up to 80%, genitourinary accounted for 13%, others account for 7%. In septic shock leading to shock, aerobic G (a) bacilli accounted for 50% of Bacteroides