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目的探讨在Ⅰ类切口手术中临床药师进行预防应用抗菌药物的干预效果。方法选取我院收治的Ⅰ类切口手术患者的入院资料200例进行分析,根据入院时间(单、双日)分为两组。试验组患者术后采用抗菌药物用药干预,对照组患者术后未采用抗菌药物用药干预,比较两组患者抗菌药物使用率、使用合理性、用药费用和用药时间等。结果试验组患者Ⅰ类切口手术后使用抗菌药物及联合用药的选择不当明显减少,用药时间以及用法用量的选择也得到明显改善;试验组患者抗菌药物费用(210±65)元,明显低于对照组的(765±130)元;试验组患者术后用药时间为(2.1±0.8)d,明显低于对照组的(4.0±0.7)d。结论临床药师对Ⅰ类切口手术中预防用抗菌药物的药学干预可降低患者抗菌药物的使用率。
Objective To investigate the clinical pharmacists in class Ⅰ incision in the prevention and treatment of antimicrobial intervention. Methods A total of 200 cases of type Ⅰ incision surgery admitted to our hospital were analyzed and divided into two groups according to admission time (single and double). Patients in the experimental group were treated with antimicrobial drugs after operation. Patients in the control group were not given antimicrobial drug intervention after operation. The antimicrobial use rate, rational use, medication cost and medication time were compared between the two groups. Results In the test group, the choice of antibacterials and combination therapy after class Ⅰ incision was significantly reduced, and the time of medication and the choice of dosage were also significantly improved. The cost of antibacterial drugs in the test group (210 ± 65) yuan was significantly lower than that of the control (765 ± 130) yuan. The duration of postoperative medication in trial group was (2.1 ± 0.8) d, which was significantly lower than that in control group (4.0 ± 0.7) d. Conclusion Clinical pharmacists can reduce the use of antimicrobial agents in the prevention of antibacterial drugs in type Ⅰ incision surgery.