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目的对比卡前列素氨丁三醇、卡孕栓、米索前列醇、缩宫素在预防产后出血发生方面的治疗效果,探讨这四种宫缩药物的特点。方法选取2011年3月至2012年3月在我院住院行剖宫产术分娩的产妇320例,随机分为四组,术中胎儿娩出后分别给予卡前列素氨丁三醇、卡孕栓、米索前列醇、缩宫素,观察各组术中、术后2h、24h的出血量、产后出血发生率及各组的药物不良反应。结果卡前列素氨丁三醇组出血量明显较其他三组少,其药物不良反应也较其他三组少,症状较轻。结论剖宫产术中联合应用卡前列素氨丁三醇和缩宫素能产生较强且持续时间较长的缩宫作用,能有效的减少术中、术后的出血量,在预防产后出血方面有确切的治疗效果。
Objective To compare the curative effect of cardoprost trometamol, carbamazepine, misoprostol and oxytocin in the prevention of postpartum hemorrhage and to discuss the characteristics of the four uterotonic drugs. Methods A total of 320 maternal women who were delivered by cesarean section in our hospital from March 2011 to March 2012 were randomly divided into four groups. The fetuses were given carboprost tromethamine, , Misoprostol, oxytocin were observed in each group intraoperative and postoperative 2h, 24h bleeding, the incidence of postpartum hemorrhage and adverse drug reactions in each group. Results Cardutilin trometamol group bleeding was significantly less than the other three groups, the adverse drug reactions than the other three groups less, the symptoms are mild. Conclusion Cesarean section combined application of carboprost tromethamine and oxytocin can produce stronger and longer duration of contraction, which can effectively reduce intraoperative and postoperative bleeding, in the prevention of postpartum hemorrhage Have the exact effect of treatment.