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在对作为试剂抗原的研究中，为尽量减少抗原中无关片段可能引起的非特异性反应，常需采用以特异性抗原表位为主的小分子肽。但有时为了增加抗原的覆盖面以提高检测的灵敏度，又需用含有多个抗原表位的融合抗原〔１，２〕。用人工合成肽成本较高，且肽与肽间的化学连接难以达到
In the study of reagent antigen, in order to minimize the possible non-specific reaction of unrelated fragments in antigen, it is often necessary to use small peptides that are mainly based on specific antigenic epitopes. However, in order to increase the coverage of the antigen so as to increase the sensitivity of the detection, it is sometimes necessary to use a fusion antigen containing a plurality of epitopes [1,2]. Synthetic peptides are more costly to synthesize, and chemical linkages between peptides and peptides are difficult to achieve