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宫颈癌的治疗方式主要是手术和放疗,即早期以手术治疗为主,中晚期大多采用同步放化疗。近年来,随着一些新型化疗药物的研制成功及临床研究,发现新辅助化疗显著地提高宫颈癌患者的手术切除率,降低了淋巴结转移、宫旁浸润和脉管癌栓等的发生比例,并且能提高5年生存率,延长患者的生存时间。本文综述了新辅助化疗对宫颈癌治疗的最新研究进展,以及多种新辅助化疗方案的疗效及其发展趋势。
Cervical cancer treatment is mainly surgery and radiotherapy, that is, early surgical treatment, mostly in the late concurrent chemoradiation. In recent years, with the successful development of new chemotherapeutic drugs and clinical research, neoadjuvant chemotherapy has been found to significantly improve the surgical resection rate and reduce the incidence of lymph node metastasis, uterine infiltration and vascular tumor thrombus in patients with cervical cancer, and Can improve the 5-year survival rate, prolong the survival time of patients. This review summarizes the recent advances in neoadjuvant chemotherapy for the treatment of cervical cancer and the efficacy and trends of various neoadjuvant chemotherapies.