论文部分内容阅读
目的:探讨体外受精-胚胎移植(IVF-ET)周期中降调节前后卵巢反应性的影响因素,寻找较好的预测卵巢反应性的指标。方法:回顾性分析贵阳医学院附属医院生殖医学中心166例首次行IVF-ET治疗患者的临床资料,根据获卵数及注射绒毛膜促性腺激素日(HCG d)的雌二醇水平将患者分为低反应组(21例)、高反应组(44例)和正常反应组(101例)。结果:3组患者的年龄、窦卵泡数、bFSH、bFSH/LH、b雌二醇、FSHd0比较差异有统计学意义(P<0.05);3组患者的bLH、LHd0、雌二醇d0和FSHd0/LHd0比较差异无统计学意义(P>0.05)。获卵数与窦卵泡数呈正相关(P<0.05),与bFSH、bF-SH/LH、b雌二醇、FSHd0呈负相关(P<0.05);与年龄不具有相关性(P>0.05)。结论:综合评价窦卵泡数、bFSH、bFSH/LH、b雌二醇和FSHd0能较好地预测卵巢不同反应性的发生;单一年龄因素预测卵巢反应性的价值有限。
Objective: To investigate the influencing factors of ovarian response before and after down regulation during in vitro fertilization-embryo transfer (IVF-ET) cycle and to find a better indicator of predicting ovarian response. Methods: The clinical data of 166 first-line IVF-ET patients treated by Reproductive Medicine Center, Guiyang Medical College Affiliated Hospital were retrospectively analyzed. According to the number of oocytes retrieved and the level of estradiol in HCG d, For the low response group (21 cases), high response group (44 cases) and normal reaction group (101 cases). Results: There were significant differences in age, antral follicle count, bFSH, bFSH / LH, b estradiol and FSHd0 between the three groups (P <0.05); bLH, LHd0, estradiol d0 and FSHd0 / LHd0 difference was not statistically significant (P> 0.05). The number of oocytes retrieved was positively correlated with the number of antral follicles (P <0.05) and negatively correlated with bFH, bF-SH / LH, b estradiol and FSHd0 (P <0.05) . CONCLUSION: The results of comprehensive evaluation of the number of antral follicles, bFSH, bFSH / LH, b-estradiol and FSHd0 can better predict the occurrence of ovarian different reactivity. The value of single age predicting ovarian reactivity is limited.