【摘 要】
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目的建立高效液相色谱法测定氟他胺片含量的不确定度分析方法。方法通过建立高效液相色谱法含量测定法的数学模型,找出影响不确定度的因素并对各个不确定度分量进行评估。结
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目的建立高效液相色谱法测定氟他胺片含量的不确定度分析方法。方法通过建立高效液相色谱法含量测定法的数学模型,找出影响不确定度的因素并对各个不确定度分量进行评估。结果计算各变量的不确定度,由此计算合成不确定度,最终给出测定结果的扩展不确定度。结论建立的方法可用于高效液相色谱法测定药物含量的不确定度分析。
OBJECTIVE To establish an uncertainty analysis method for the determination of flutamide tablets by high performance liquid chromatography. Methods By establishing a mathematical model for the determination of high performance liquid chromatography, the factors influencing the uncertainty were determined and the components of each uncertainty were evaluated. Results The uncertainty of each variable was calculated, the composite uncertainty was calculated, and finally the expanded uncertainty of the determination results was given. Conclusion The established method can be used to analyze the uncertainty of drug content by high performance liquid chromatography.
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