论文部分内容阅读
络合剂在分析化学中的应用以及一般原理,最近以来,大家研討得非常热烈,也先后在国內外的許多書刊杂誌上發表,它的优点是手绩簡便,操作快捷,既能提高工作效率,又能确保檢驗質量,药品分析中固有的一些方法,許多都可以採用络合剂滴定,本文仅拟就几种常用药物的絡合剂滴定及与經典方法的对照实驗方面作一簡單介紹,以供药工同志們参考。一、乳酸鈣类: 精密称取檢品0.2克,加蒸餾水約20毫升,加热使溶,冷却,加入10毫升NH_4OH-NH_4Cl緩冲溶液,0.1克銘黑T指示剂及Mg~(++)溶液一滴,以0.05M乙二胺四乙酸鈉(以下簡称E.D.T.A.)溶液滴定至显藍色,並同时作一空白,以求得一滴Mg~(++)所消耗的E.D.T.A.毫升数。若系片剂,可取相当于1.5克乳酸鈣的檢品粉末,加水約100毫升、盐酸8毫升,在沸水
Complexing agents in the analytical chemistry and the general principles of the recent study has been very enthusiastic, but also in many domestic and foreign books and magazines published its advantages are simple performance, quick operation, both to improve work efficiency , But also to ensure the quality of testing, some of the methods inherent in drug analysis, many can use complexing agent titration, this article intends only to several commonly used drugs complexing agent titration and comparison with the classical method of a simple experiment to make a brief introduction For the pharmaceutical comrades reference. First, the calcium lactate: accurately weighed 0.2 grams of seized goods, add about 20 ml of distilled water, heated to dissolve, cool, add 10 ml NH_4OH-NH_4Cl buffer solution, 0.1 g Ming black T indicator and Mg ~ (++) A drop of solution, with 0.05M EDTA (EDTA) solution titration to a significant blue, and at the same time as a blank, in order to obtain a drop of Mg ~ (++) consumption of EDTA ml. If the Department of tablets, preferably equivalent to 1.5 grams of calcium lactate test powder, add water about 100 ml, hydrochloric acid 8 ml in boiling water