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目的探讨脑动脉狭窄或闭塞患者侧支循环建立相关危险因素。方法脑动脉狭窄或闭塞患者175例,均行全脑血管造影术,分析脑动脉狭窄程度与侧支循环建立的关系及其影响因素。结果侧支循环代偿良好率随脑动脉狭窄程度的增加而升高。单因素分析结果显示代偿良好组吸烟、糖尿病、高脂血症、高血压比例和纤维蛋白原水平明显高于代偿不良组(P<0.05);多因素logistic回归分析结果显示,吸烟,合并糖尿病、高脂血症、高血压,纤维蛋白原是脑动脉狭窄侧支循环的危险因素。结论侧支循环代偿良好率随脑动脉狭窄程度的增加而升高;吸烟,合并糖尿病、高脂血症、高血压,纤维蛋白原是脑动脉狭窄侧支循环的危险因素。
Objective To explore the related risk factors of collateral circulation in patients with cerebral stenosis or occlusion. Methods A total of 175 patients with cerebral stenosis or occlusion underwent cerebrovascular angiography. The relationship between cerebral stenosis and collateral circulation and its influencing factors were analyzed. Results collateral circulation compensatory good rate increases with the degree of cerebral artery stenosis increased. Univariate analysis showed that smoking, diabetes, hyperlipidemia, hypertension and fibrinogen were significantly higher in compensated group than those in decompensated poor group (P <0.05). Multivariate logistic regression analysis showed that smoking, Diabetes mellitus, hyperlipidemia, hypertension and fibrinogen are risk factors of collateral circulation in cerebral artery stenosis. Conclusion The good rate of compensatory collateral circulation compensatory rate increases with the degree of cerebral artery stenosis. Smoking, diabetes mellitus, hyperlipidemia, hypertension and fibrinogen are the risk factors of collateral circulation in cerebral artery stenosis.