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嗜碱性白细胞胞浆中含有嗜碱性染色的颗粒,核的大小和形状很像嗜中性白细胞。嗜碱性白细胞占血液中白细胞的1％,由于分离精制的困难,对其生理生化特性以及其在机体防御机制上的重要性认识较晚。但在研究人类疾病过程中IgE的作用时,对嗜碱性白细胞的IgE受体,以及通过IgE而发生的细胞颗粒内容物的释放进行了研究,认识到做为对抗后的应答,嗜碱性白细胞放出炎症介质,激活补体、血凝、激肽等血清瀑布系统(Serwm cascade syslem),并与其他细胞相互作用,在炎症时起重要作用。
Basophilic leukocyte cytoplasm contains basophilic staining of particles, the size and shape of the nucleus is very much like neutrophils. Basophils account for 1% of the white blood cells in the blood. Due to the difficulty in separation and purification, their physiological and biochemical characteristics and their importance in the body’s defensive mechanism are late recognized. However, in studying the role of IgE in human disease, studies have been conducted on the release of IgE receptors for basophils and cellular granule contents by IgE, and as a response to post-challenge, basophilicity Leukocytes release inflammatory mediators and activate Serum cascade syslem such as complement, hemagglutination and kinin, and interact with other cells to play an important role in inflammation.