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贵州省某地１９７６年发生８７７例燃用高砷煤引起中毒，２０年的防治结果表明他们的外环境及人体尿、发含砷量、病情、新发病例等均有显著差异，但病人的皮肤损害病征检出率却无显著差异；而味觉、肝区痛、眼部疾患、胃肠道疾病、肢端麻木等非皮肤病征有显著差异。虽所有患者均接受过多次系统排砷治疗，但病情的下降显著以停用高砷煤，改善了环境的为最好，故认为改善病区的高砷环境是防病的首要措施。同时提出本病的治愈标准不应该以皮肤损害病征为主要指标，并探讨了非皮肤病征作指标的可能性。
In 1976, 877 cases of high-arsenic coal poisoning occurred in a certain place in Guizhou Province. The results of 20 years of prevention and treatment showed that there were significant differences in their external environment and human urine, hair arsenic content, disease and new cases, but the patients’ There was no significant difference in the detection rate of skin lesion symptoms; however, there were significant differences in non-dermatological signs such as taste, liver pain, eye diseases, gastrointestinal diseases and numbness of limbs. Although all patients had received systematic arsenic treatment for many times, their condition was significantly reduced to disable high-arsenic coal and improve the environment as the best. Therefore, improving the arsenic environment in the ward is the most important preventive measure. At the same time, the cure criteria of this disease should not be taken as the main indicators of skin lesions, and explore the possibility of non-dermatological indicators.