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分析５１例药源性中性粒细胞减少症和缺乏症。前者３６例，后者１５例。其病因以解热镇痛药居首，为２１．５％，其后依次为甲巯咪唑、Ｈ２受体阻滞剂、抗生素、磺胺及其它抗菌药，分别为１９．６％、１７．６％，１５．７％，１１．７％。其它少见的有抗结核药、氯丙嗪、苯妥英钠、氯磺苯脉、普鲁卡因胺、卡托普利等。死亡３例，均为粒缺患者，占粒缺的２０％。因此，合理用药、严格掌握适应症、使用过程中严密观察血象变化，是减少发生率和病死率的关键。
Analysis of 51 cases of drug-induced neutropenia and deficiency. The former 36 cases, the latter 15 cases. The etiology of antipyretic and analgesic drugs topped 21.5%, followed by methimazole, H2 blockers, antibiotics, sulfonamides and other antibacterial drugs were 19.6%, 17.6 %, 15.7%, 11.7%. Other rare anti-TB drugs, chlorpromazine, phenytoin, chlorpheniramine pulse, procainamide, captopril and so on. 3 cases died, all patients with granuloma, accounting for 20% of the granuloma. Therefore, the rational use of drugs, strict indications, the use of close observation of changes in blood is to reduce the incidence and mortality key.