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The mechanism that DNA hypomethylation leads toactivation of oncogene and occurrence of malignantneoplasm is being increasingly recognized byresearchers. Normal DNA methylation playsimportant role in stabilizing the phenotype of cell.DNA methylation status reduction and/or patternalteration are related to activation and abnormallyhigh expression of some oncogenes and cellularmalignancy. c-fms oncogene encodes for colonystimulating factor 1 receptor(CSF-1R), c-fms/
The mechanism that DNA hypomethylation leads toactivation of oncogene and occurrence of malignantneoplasm is being increasingly recognized by researchers. Normal DNA methylationsimport important role in stabilizing the phenotype of cell.DNA methylation status reduction and/or patternalteration are related to activation and abnormallyhigh expression of some oncogenes and Cellularmalignancy. c-fms oncogene encodes for colonystimulating factor 1 receptor(CSF-1R), c-fms/