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一些学者认为ECHO病毒是感染性多发性神经炎的病原之一。临床资料:1978年6月间,建昌县喇嘛洞公社小三家子大队暴发一起多发性神经炎,共34例,发病率为6.7％,10～20岁组发病最高,有被雨淋和受凉的诱因。起病急骤,有不同程度的运动障碍,多为下肢瘫痪,双侧及单侧者占64.8％,尚有两例出现进行延髓性麻痹,其中一例死亡。此外尚有“手套”和“袜套”型感觉障碍,躯干肢体肌肉疼痛,或伴有低烧、头晕、心慌等。病毒分离与鉴定:采用原代人胚肾细胞按常规法进行分离,从9例病人粪便标本中分离出8株病毒。对分离株做了Polio混合血清中和试验、乳鼠试验、耐酸和耐乙醚试验。根据细胞病变特点,不被
Some scholars believe that ECHO virus is one of the pathogens of infectious polyneuritis. Clinical data: In June 1978, Jianchang County Lama cave commune small three sub brigade outbreaks with multiple neuritis, a total of 34 cases, the incidence was 6.7%, 10 to 20-year-old group had the highest incidence of being rain and cold The incentive. Sudden onset, there are varying degrees of dyskinesia, mostly lower limb paralysis, bilateral and unilateral accounted for 64.8%, there are two cases of bulbar paralysis, of which one case of death. In addition there are “gloves” and “socks” type of sensory disturbance, trunk and limb muscle pain, or accompanied by low fever, dizziness, palpitation and so on. Virus Isolation and Identification: The primary human embryonic kidney cells were isolated by routine methods and eight viruses were isolated from the stool specimens of nine patients. Isolates were made Polio mixed serum neutralization test, suckling rats, acid and ether resistance test. According to the characteristics of cytopathic lesions, not be