Effects of HLEC on the secreted proteins of epithelial ovarian cancer cells prone to metastasize to

• 作 者: Xin-Ying Zhang Fu-Qiang Yin Li
• 机 构: TheCancerHospitalAffiliatedtoGuangxiMedicalUniversity,TheExperimentCenterofTheGuangxiMedicalUniversi
• 出 处: 癌症生物学与医学：英文版
• 发表日期: 2013年4期
• 关键词: 卵巢癌细胞 淋巴结肿大 分泌蛋白 上皮 ELISA检测 生物信息学 SPARC IGFBP Ovarian cancer tumor microenviron
• 基金项目: supported by the National Natural Science Foundation of China (Grant No. 81060218),Guangxi Natural Science Foundation (Grant No. 2012GXNSFAA053157)

Objective:To study explores the effect of HLEC on the secreted proteins of epithelial ovarian cancer(EOC)cells(SKOV3-PM4)with directional highly lymphatic metastasis.Methods:Supernatants of four groups of cultured cells,namely,SKOV3(A),SKOV3+HLEC(B),SKOV3