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Fyodorov首先创制包扎角膜的胶原角膜罩(collagen corneal shield),用于治疗角膜擦伤和角膜屈光性手术后的处理。这种胶原罩像角膜接触镜,用猪巩膜胶原制成,其胶原成分与人角膜很类似。它不仅能起到治疗性或包扎性角膜接触镜的作用,而且当它与麻醉液、泪液和抗生素溶液水化以后,安置于眼上,就能变软,形成角膜的形状,并缓慢溶解。这种胶原罩(Bio-Cor)现由美国佛罗里达州Bausch&Lomb厂生产,有3种类型,在人眼的溶解时间分别约为12、24和72小时(Bio-Corl2,Bio-Cor24,Bio-Cor72)。在此时间内,它能润滑、保护角膜不被眼睑擦伤,促进上皮愈合,比结膜下注射能更有效地释放抗生素,而且舒服,不像其它治疗性角膜接触镜那样“吸”在
Fyodorov first created a bandaged corneal collagen corneal shield for the treatment of corneal abrasions and corneal refractive surgery. This collagen cover, like a contact lens, is made of porcine sclera collagen and has a collagen composition similar to that of a human cornea. Not only does it function as a therapeutic or occlusive contact lens, it softens, forms the cornea, and dissolves slowly when it is hydrated with anesthetic fluids, tears, and antibiotic solutions. This type of collagen cover (Bio-Cor) is currently manufactured at the Bausch & Lomb plant in Florida, U.S.A. There are 3 types that dissolve in the human eye for about 12, 24 and 72 hours respectively (Bio-Corl2, Bio-Cor24, Bio-Cor72 ). During this time, it lubricates, protects the cornea from eyelid abrasions, promotes epithelial healing, releases antibiotics more efficiently than subconjunctival injections, and is comfortable, unlike other therapeutic contact lenses that “suck” in