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人工核酸酶是一类具有限制性内切酶的功能、能高效高选择性地催化水解ＤＮＡ或ＲＮＡ的断裂工具。它们一般由核酸结构识别系统及催化断裂系统组成，将两种功能有效地结合起来，可模拟核酸的酶切反应。本文综述了稀土及其配合物对核酸的断裂作用，并对其断裂机制进行了探讨
Artificial nucleases are a class of restriction endonucleases that efficiently and highly selectively catalyze the cleavage of DNA or RNA. They generally consist of a nucleic acid recognition system and a catalytic rupture system, which combine the two functions effectively to mimic the enzymatic cleavage reaction of nucleic acids. This article reviews the rupture effect of rare earths and their complexes on nucleic acids, and explores the mechanism of rupture