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越来越多的研究表明,肿瘤体积与传统TNM分期相比,是一项更具优势的预测指标。人乳头瘤病毒(HPV)阳性的口咽鳞癌(oropharyngeal SCC)更容易出现包膜内淋巴结转移,常常出现转移灶很大,而原发灶很小。该文旨在对53例接受化疗及调强放疗(IMRT)的HPV阳性口咽SCC患者进行评估。结果:平均2年总生存率(OS)和无病生存率(DFS)分别为92.2%和83.6%。淋巴结分级与OS(P=0.096)及DFS(P=0.170)
A growing body of research shows that tumor volume is a more predictive predictor than traditional TNM staging. Human papillomavirus (HPV) positive oropharyngeal squamous cell carcinoma (oropharyngeal SCC) is more prone to en bloc lymph node metastasis, often showing a large metastasis, and the primary tumor is small. The aim of this study was to evaluate 53 patients with HPV-positive oropharyngeal SCC receiving chemotherapy and intensity-modulated radiation therapy (IMRT). Results: The average 2-year overall survival (OS) and disease-free survival (DFS) were 92.2% and 83.6%, respectively. Lymph node grading was associated with OS (P = 0.096) and DFS (P = 0.170)