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目的：有关实验性口服或静脉注射急性暴露氟对机体影响的报道较多，但由于氟离子可迅速从肾脏排泄而难以在血中维持较高浓度，因而也不易掌握一定浓度长期暴露的影响。为此，本文作者通过持续静脉给予氟化物探讨了其对肾的影响。 方法：将１１周龄的Ｗｉｓｔａｒ系雄性大鼠（共
OBJECTIVE: There are many reports on the effects of experimental oral or intravenous acute exposure to fluoride on the body. However, it is not easy to grasp the long-term effects of certain concentrations due to the rapid excretion of fluoride from the kidneys and the difficulty of maintaining high concentrations in the blood. To this end, the authors investigated their effects on the kidneys by continuous intravenous administration of fluoride. Methods: Wistar male rats 11 weeks old (total