Granulocyte colony-stimulating factor increases extracellular glutamic acid uptake and suppresses fr

• 作 者: Shengzhe Zheng Lei Song Lei Lu
• 机 构: DepartmentofNeurology
• 出 处: 中国神经再生研究：英文版
• 发表日期: 2011年2期
• 关键词: 粒细胞集落刺激因子 自由基损伤 谷氨酸 实验模型 硬化 细胞外 谷胱甘肽过氧化物酶 免疫组织化学方法 amyotrophic lateral sclerosis

Excitatory amino acid toxicity and free radical damage play important roles in amyotrophic lateral sclerosis.Granulocyte colony-stimulating factor(G-CSF)protects nerve cells exposed to high-concentrations of glutamic acid,suggesting positive effects in th